Novartis AG

Clinical Trials Drugs (Pharmaceuticals)Heart Krumholz, Harlan M Maron, David J Novartis AG

September 11, 2026 Gina Kolata

How Did a Heart Drug With So Much Promise Fall So Flat?

Cardiologists are struggling to figure out why a drug that should have prevented heart attacks didn’t work at all.

The Heart Drug Pelacarsen Fails, Shocking Novartis and Cardiologists

Doctors were hopeful the drug, which was being tested in a large clinical trial by Novartis, was going to be a powerful new tool to fight heart disease.